Appsilon collaborated with a leading pharmaceutical company to modernize their Posit stack, ensuring GxP compliance while addressing regulatory risks and operational challenges. Recognizing that a simple upgrade risked disrupting data science workflows and increasing technical debt, Appsilon devised a migration strategy, replicating the environment with enhanced architecture. They integrated the system with Kubernetes, despite compatibility issues, to enable scalability, and standardized three diverse working environments for consistency. Utilizing Ansible scripts, they streamlined installation, configuration, and audit processes. In addition to establishing a compliant, scalable platform, Appsilon offered comprehensive documentation and knowledge transfer, empowering client teams to reduce support dependencies. This solution not only met compliance standards but also enhanced operational efficiency, providing a robust, future-proof foundation for the client's data science endeavors.